ML was a promoter of the scientific field of Information system. This field has created the knowledge to set up an articulated chain of knowledge between the world of human activities as management and the world of informatics. Nowadays there a lot of information systems in all the parts of our Society. The new challenges are about the situations of added values. That is the domain of Service Science, a very innovative domain with a lot of exciting research questions in many academic sectors, in particular management and information technologies, because of its transdisciplinary characteristics. Behind the Service Science, there are deep transformations of our Society and challenging opportunities for neew activities.